Discovery & Development US 2026
Hilton San Diego Bayfront, CA
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Agenda
High Throughput Screening
Industry PresentationThe Power Of Partnerships: Aligning Pharma, Biotech, And Academia To Accelerate Development & Innovation
Panel Discussion• Bridging cultures and goals
• Shared resources and expertise
• Accelerating translation
• How partnerships can streamline moving discoveries from the lab to clinical development and market
Automation & AI: Examples From Recursion
Industry PresentationBreaking The First In Class Barrier In Small Molecule Drug Discovery
Industry PresentationThe Target Validation Frontier: Multi-Omics And AI In Drug Discovery
Panel Discussion• Standardization and integration of omics datasets across platforms and labs
• Balancing computational predictions with experimental validation
• Challenges in scaling multi-omics for high-throughput target ID
• Regulatory considerations for omics-informed drug development
• Where AI fits in multi-omics pipelines
Foundation Models For Chemistry: A New Paradigm In Hit Discovery And Lead Optimization
Industry PresentationSolving The Right Problems – Finding AI’s Value In Drug Discovery
Panel Discussion• How to use AI/ML to solve drug discovery problems
• Success metrics
• Overcoming validation hurdles
CNS Drug Repurposing Using AI/ML Frameworks
Industry PresentationDelivering Therapies Across The Blood-Brain Barrier
Panel Discussion• Developing optimized BBB models for drug discovery
• Predicting future
• Recent technological advancements & platforms
• Challenges and unities for the delivery of biopharmaceuticals
• Using nasal to brain route
Novel Hit Identification Techniques
Industry PresentationTechnological Advancements For The Discovery Of New Targets
Industry PresentationDiscovery Of Orally Efficacious Inhibitors Of A Viral Macrodomain
Industry PresentationMacrodomains are previously undrugged ADP-ribosylhydrolases
Standard cell models of infection are not useful for screening/ranking macrodomain inhibitors
Airway organoid and primary macrophage models proved more sensitive to macrodomain inhibitors
The discovery of the first orally efficacious SARS-CoV2 macrodomain inhibitor AVI-6451 will be detailed
Astellas's TPD Strategy and Updates from the KRAS Degrader Pipeline
Industry PresentationAn overview of Astellas’ targeted protein degradation strategy and portfolio, highlighting recent progress from the KRAS degrader ASP3082 and the development of our pan-KRAS degrader program ASP5834.
Pushing The Boundaries Of Target Discovery In 2026 & Beyond – New Technologies, Approaches, Industry Directions
Panel Discussion• The evolution of modalities
• When to pursue small molecules, ADCs, protein degraders, RNA modalities, or multi-modal approaches
Applications Of High-Throughput Data Collection In AI/ML
Industry PresentationMulticellular Perturbation Models For Drug Discovery
Industry Presentation• AI architecture for virtual clinical trials and phenotypic in silico drug discovery
• Building TRAILBLAZER, the first AI foundation model built specifically for multicellular biology, capable of simulating patient-level treatment outcomes
• Case studies of phenotypic in silico drug discovery and modeling multicellular patient responses to treatments
Generative AI-Guided Selections for GPCR Antibody Discovery
Industry PresentationIntegrating Human-Centric Biology, AI, & New Approach Methodologies For Phase 1 Clinical Trials
Industry PresentationThe Degrader & Glue Landscape In 2026
Industry PresentationNovel Models For ADME-Tox Research
Industry PresentationAdvancing Multimodal Omics Data In Drug Discovery
Industry PresentationAI In Drug Discovery
Industry PresentationScaling Chemical Space: AI-Driven Paradigm Shift In Target And Hit Discovery
Industry PresentationFrom Screening to Pharmacology: Optimization of Molecular Glue Degraders
Industry PresentationWhere Smart Capital Meets Science: Investing In The Next Wave Of Drug Discovery Innovation
Panel Discussion• How investors evaluate emerging drug discovery technologies
o AI in drug discovery
• What drives funding decisions in a shifting biotech market
• Where capital is flowing next
• How investor are looking at non-dilutive founding
Lab Digitalization & AI
Industry PresentationBeyond The Hype: AI, Data & The Industry Shift In Drug Discovery R&D
Panel Discussion• How industry dynamics are reshaping pharma R&D strategy & decision-making
• Digital transformation, AI & data-driven labs of the future
• What leaders need to prioritize to turn innovation into real scientific & business impact
Challanges Of Adopting NAMs: Regulatory & Technical Bottlenecks
Roundtable Discussion• Navigating regulatory uncertainty, validation standards, and industry confidence when integrating NAMs into development pipelines
• Overcoming technical hurdles including model reproducibility, data translation, scalability, and cross-platform comparability
Hit Finding And Characterization In Covalent Drug Discovery
Industry PresentationStrategic application of complementary approaches for covalent hit finding in vitro and in cells
Chemoproteomics applications for hit characterization and determination of novel ligandable sites on targets of interest
Library considerations for covalent hit finding at Novartis
Women In Drug Discovery & Development
Panel Discussion• Exploring pathways to leadership, career progression, and influence for women across drug discovery and development organizations
• Addressing barriers to advancement while sharing strategies to foster mentorship, sponsorship, and greater diversity in scientific innovation and decision-making
From Innovation to Impact: Market Strategies Driving the Next Wave of Drug Delivery Technologies
Panel Discussion• What actually defines a “successful” delivery innovation in the market?
• From lab breakthrough to commercial product: where do most strategies fail?
• Pharma vs biotech vs academia: who owns the pathway to market?
• Market access and reimbursement as the real gatekeepers of innovation
Solution Provider Presentation
Solution Provider PresentationSolution Provider Presentation
Solution Provider PresentationSolution Provider Presentation
Solution Provider PresentationThe Use Of Quantum Mechanics In The Future Of Drug Discovery
Roundtable Discussion• Implementing AI to aid in generative design
• Looking to the future
Validation & Regulations For NAMs
Industry PresentationSponsor Presentation
Solution Provider PresentationSubmission required
Solution Provider Presentation
Solution Provider PresentationHow To Use NAMs
Panel Discussion• Organoids and organ-on-chip models
• In vitro disease modelling
• Toxicity and safety screening
• Disease biology
• PK/PD and toxicity modelling
• In silico models
• Implementation and application of NAMS
Solution Provider Presentation
Solution Provider PresentationSolution Provider Presentation
Solution Provider PresentationSolution Provider Presentation
Industry PresentationPartnerships, Platforms Or Acquisitions: What Is The Winning Model For Brain Health Innovation?
Panel Discussioncollaboration models that actually work
• When to partner vs acquire vs build internally
• Data-sharing in a competitive landscape
• Public-private partnerships in USA: success stories & failures
Submission required
Solution Provider PresentationSubmission required
Integrating AI/ML And Automation In Discovery Chemistry
Industry PresentationOrgan-On-Chip & Organoid Applications In Viral Infections
Industry PresentationAI/ML, Specializing In Omics & Systems Biology
Industry PresentationMulti-Omics & Predictive Models
Industry PresentationDevelopment Of Small Molecule Huntington’s Disease Therapeutics With A Novel Mechanism Of Action
Industry Presentation• Hit identification in a phenotypic screen
• Demonstration of selective degradation of mutant huntingtin and cellular disease phenotype reversal
• PK/PD relationship in preclinical mouse models
Dealing With High Manufacturing And Product Costs In The Gene Therapy Space
Roundtable DiscussionSmall Molecules To Mitigate Cisplatin Toxicities Including Hearing Loss
Industry PresentationAI Rewiring The Future Of Drug Discovery
Industry Presentation• Taking a deep dive into generative AI for molecular design to illustrate individual methods that have transformative implications
• Putting it all together – active learning and multi-property optimisation for multiple drug properties
• Using AI to integrate early and late-stage considerations – agentic AI approaches
• How do we collaborate across the industry to develop these frameworks?
Targeted, Long-Term Durability & Release
Industry PresentationReinventing CNS Drug Discovery With AI And Human Brain Organoids
Industry PresentationGenomics Technologies For Neurological Indications
Industry PresentationAI & In Silico Tools In Formulation Development
Roundtable DiscussionNew Data Tools For Taking Biomarkers To Clinical Trials
Industry PresentationCritical Attributes For Successful mRNA Based Drug Products
Roundtable Discussion• What are critical elements for drug substance?
• What makes a good delivery system?
• How sustainable can mRNA-based drug products be?
Afternoon Break & Refreshments
Lunch Break
Morning Break & Refreshments
Close of Day One & Networking Drinks Reception
Lunch Break
End of Event
Morning Break & Refreshments
Regulatory Acceptance Of Human On A Chip Systems For Neurological Diseases And Conditions
Industry PresentationBridging The Translational Gap In Neurodegenerative Drug Development
Roundtable Discussion• Building more predictive preclinical programs using human-relevant models and biomarkers
• Leveraging AI to improve target prioritization, patient stratification, and clinical trial design
• Overcoming the biggest barriers to translating promising discoveries into clinical success
• What recent neuroscience programs have taught us about reducing late-stage attrition
Single-Cell And Spatial Omics Approaches For Functional Genomics In Neuroscience
Industry PresentationHow Early Should Developability And Drug Delivery Considerations Influence Target Selection And Lead Optimization Decisions?
Roundtable Discussion• What risks emerge when delivery and developability are addressed too late in the discovery process?
• Should delivery feasibility be a formal criterion when prioritizing targets?
• How can discovery and development teams collaborate earlier to improve program success rates?
From Discovery to Delivery: Turning Scientific Innovation into Commercial Success
Roundtable Discussion• What separates promising science from commercially viable innovation?
• Common pitfalls in translating research into therapeutics
• Building collaborations between academia, biotech, and pharma
• How startups can position themselves for investment and strategic partnerships
Delivery-Driven Innovation: Unlocking The Potential Of Next-Generation Therapeutics
Keynote• When delivery—not the molecule—is the bottleneck
• Overcoming barriers across peptides, CNS therapies & infectious diseases, and emerging modalities
• From AI to clinical use
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