Analytical and Chemical Enhancements to Improve Efficacy and Accuracy of Therapeutic Oligonucleotides
See how top pharma players are addressing impure, unstable, and off-target oligos
Boosting the Efficacy of Safe, Scalable, & Precise Vaccines
Innovations in mRNA Technology, RNA Therapeutics, and Cancer Immunotherapy for 2024
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Tumbler: A Highly Customizable Antibody Optimization Suite
On-demand presentation, presented by Michali Izhaky, Bioinformatics Scientist at Charles River
Leading Innovations in Fab, ScFv, & VHH Production and Engineering
On-demand webinar presented by Dr Jiansheng Wu, Head of Protein Sciences and Vice President at WuXi Biologics
Advancing Immunotherapy: The Critical Role of GMP-Grade Cytokines in Cell Therapy
On-demand webinar presented by Ritwika Biswas, Field Application Scientist at Sino Biological
Optimizing Bispecific Antibody Production: From Identifying Optimal Pairings to Scale-up Processes
On-demand webinar presented by Dr Jiansheng Wu, Head of Protein Sciences and Vice President at WuXi Biologics
Unlocking the Future of Immune Cancer Therapy
A concise report featuring insights from the prominent though leaders of Immuno 2024.
Drug Discovery & Development
Experiments Link Gut Microbiome and Graft-versus-Host Disease
Modulating the gut microbiome may be a key to preventing GvHD and stopping relapse.
Bioanalysis
Overcoming the Hurdles: Navigating the Challenges of Bioconjugate Development
Bioconjugate development, exemplified by ADCs such as T-DM1 and Mylotarg, tackles issues like stability and specificity, benefiting from innovative solutions and services to enhance therapeutic precision in biologics.
Gene Therapy Development
Safety in Viral Vectors and Viral Clearance: Ensuring Efficacy and Security in Biopharmaceuticals
We discuss the challenges and safety measures in using viral vectors for gene therapies, focusing on vector selection, safety testing, quality control, and contamination prevention, highlighting their importance for the success of advanced medical treatments.
Oligo Chemistry
New Approach to Oligo-Peptide Synthesis from Novo and Aarhus University
The collaboration could unlock the more cost-effective synthesis of oligonucleotide-peptide conjugates.
Drug Discovery & Development
UPenn Medicine Presents Promising Phase I CAR T Trial with Novel Binding Mechanism
The CAR T therapy targets CD19 closer to the cell membrane and has demonstrated remarkable efficacy in its Phase I clinical trial.
Tumour Microenvironment
Understanding and Overcoming the Immunosuppressive TME
Explore the intricate world of the immunosuppressive tumor microenvironment (TME), a key player in cancer progression and treatment resistance
Manufacturing & Bioprocessing
Proactive Approaches to Cell Culture Media and Process Control Strategies
Merck invests $25 million in a Kansas cell culture media plant, aiming to meet rising demand for advanced therapeutics while aligning with sustainability goals.
Antibody & Protein Engineering
The Current Landscape of ADC Approvals and Market Trends: Q&A With Mahendra Deonarain, CEO of Antikor Biopharma
While a recent spike in ADC approvals may not last forever, Antikor Biopharma’s Mahendra Deonarain asserts that antibody-drug conjugates are here to stay.
Manufacturing & Bioprocessing
In Conversation With… Sophie Mountcastle, Network Manager, Innovation Hubs for Gene Therapies
Here, we discuss the crucial role of a collaborative network for gene therapy development across the UK and some of the successes seen to date.
Stem Cell Therapy
Comparing Allogeneic and Autologous Stem Cell Transplantation Approaches
While both allogeneic and autologous cell therapies have seen a recent boom, the two approaches differ in terms of scale and customisation.
Manufacturing & Bioprocessing
Improving Control Strategies for Bioprocessing & Cell Culture
Discover advanced monitoring, environmental controls, mathematical models, PAT tools, and sensor technologies shaping the future of biopharmaceuticals
Antibody & Protein Engineering
Introducing the Development and Clinical Landscape of Bi and Multispecific Antibodies
While bispecific antibodies target two specific entities, multispecific antibodies can target more than two. The use of these engineered antibodies offers the potential for enhanced therapeutic strategies by simultaneously addressing multiple aspects of a disease.