.jpg)
Process Challenges in ATMP Development: Overcoming Hurdles for Successful Manufacturing
- Scalability & Manufacturing Complexity
- Supply Chain Management & Logistics
- Regulatory Compliance & Quality Assurance
Progress and Prospects for Cancer Vaccines
-
Various vaccine approaches including peptides, proteins & mRNA
-
Immunotherapies & anti-cancer therapies
Leading Innovations in Fab, ScFv, & VHH Production and Engineering
Presented by Jiansheng Wu, Ph.D., Head of CRO Services, Vice President
Antibody fragments such as Fab, ScFv, and VHH are transforming the landscape of antibody drug development, used both as independent therapeutics and key components in bispecific antibodies. However, producing and engineering these fragments comes with unique challenges like low yields, impurities, and stability concerns. In this webinar, we’ll showcase cutting-edge solutions to these challenges, offering fresh insights into molecular engineering, high-titer CHO expression systems, and targeted purification techniques. These approaches are specifically tailored to address the unique challenges of Fab, ScFv, and VHH.
What you’ll gain from this webinar:
- Innovative methods to overcome production hurdles such as low yield, throughput limitations, and impurities.
- Advanced molecular engineering strategies to reduce aggregation and improve yield.
- Fragment-specific optimization strategies for Fab, ScFv, and VHH to maximize production efficiency and ensure higher purity.
Advancing Immunotherapy: The Critical Role of GMP-Grade Cytokines in Cell Therapy
Presented by Ritwika Biswas, Field Application Scientist
As immunotherapy progresses, GMP-grade cytokines are increasingly vital for enhancing the effectiveness of cell-based therapies. Cytokines such as Interleukin-2 (IL-2), which drives the expansion and activation of T cells in CAR-T cell therapies, Interleukin-7 (IL-7), which supports T cell survival and proliferation, and Interleukin-15 (IL-15), which stimulates the activity of natural killer (NK) cells and T cells, are key components in these therapeutic approaches. By meeting stringent regulatory standards, these GMP-grade cytokines ensure purity, consistency, and safety, making them crucial in developing scalable, effective treatments for diseases like cancer and autoimmune disorders.
This webinar will explore the critical role of these cytokines in cell therapy, from their use in expanding immune cells to their impact on clinical manufacturing. Attendees will learn how GMP-grade cytokines are improving therapeutic outcomes while maintaining the highest levels of safety and quality in clinical applications.
Speaker Bio
Ritwika joined Sino Biological in 2022 as a Product Scientist. Currently she works as a Field Application Scientist for the eastern and central US regions. Prior to joining Sino Biological, Ritwika was a Graduate Research Assistant at the University of Houston, specializing in using organoids for drug discovery in the field of Inflammatory Bowel Disease (IBD). Her expertise encompasses Cytokines, Organoid Culture, Disease Modeling, and Cancer Therapies.