Resources

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Manufacturing & Bioprocessing

Implementing Process Analytical Technology into Cell and Gene Therapy Manufacturing

A recent study shows that a novel refractometry-based PAT system monitors metabolic activity during CGT production, revealing insights into optimising bioprocesses.
Immuno-Oncology

Patients Enter Clinic for Phase III mRNA Immunotherapy for High Risk Melanoma

The trial will test the world's first mRNA-based personalised immunotherapy for melanoma.
Stem Cell Therapy

In Conversation with Stephen Sullivan, COO of iPSirius

Cell & Gene 2024 Conference Producer Anya Chuykov met with Stephen Sullivan, COO of iPSirius, to discuss the advancements being made by iPSirius, and their unique proprietary technology working to treat aggressive forms of cancer.
Immunotherapy (Non-Oncology)

First Patient Dosed with NK Cell Therapy for the Treatment of an Autoimmune Disease, Lupus Nephritis

The NK cell therapy is being trialled in combination with monoclonal antibody therapy and hopes to induce B-cell depletion.
Peptide Chemistry

Sustainable Pharma: Celebrating Progress and Confronting Challenges on Earth Day

Earth Day marks a moment to reflect on the planet's health and our collective efforts to nurture it. To celebrate Earth Day, this article will examine the strides the pharmaceutical and biotechnology industry has made towards fostering sustainable and green practices alongside the challenges.
Antibody & Protein Engineering

Rapid Analytical Approach for Biologics Characterization Using Mass Photometry

On-demand webinar featuring Dr Racha Majed, Technical Sales Specialist, Refeyn
NextGen Therapeutics

Merus's Preclinical Bispecific Zeno Demonstrates Efficacy in Cancer Models

Zeno interrupts the dimerization of HER2 and HER3 and prevents NRG1/HER3 tumour signalling.
Drug Discovery & Development

Positive Results from iNKT Cell Therapy Clinical Trial for COVID-19 ARDS

The small exploratory trial shows signs that iNKT cells can improve the survival rate of respiratory distress from COVID-19.
Cell Line Development

UNIVERCell: Engineering Red Blood Cells for Targeted Therapy

Scarlet Therapeutics uses genetic manipulation of red blood cells to carry a higher load of therapeutic proteins to help treat rare metabolic diseases.
Cell Line Development

Enhancing Gene Editing Efficiency: Multi-Tailed mRNA Integration in CRISPR-Cas9 Systems

A study conducted by the Broad Institute and the Massachusetts Institute of Technology (MIT) demonstrated that when multi-tailed mRNAs were integrated into a CRISPR-Cas9 system they proved to be more efficient gene editors than unmodified mRNA.
Oligo Chemistry

Japanese Team Successfully Skip Abnormal Gene In Vitro With Antisense Oligonucleotide for BPAN

Rare disease BPAN currently has no treatment options, this new research investigates whether antisense oligonucleotide therapies could be the answer to address this unmet need.
Oligo Chemistry

Oligo Sequencing Technologies - What Methods and Techniques Are Utilized in the Pharmaceutical Industry?

Oligo sequencing revolutionizes biologics research, ensuring accurate analysis of oligonucleotides. Biologics by Oxford Global explores methods, safety, sustainability, and future trends. Despite challenges, advancements promise exciting opportunities for scientific discovery.

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