Accelerating Biologics Discovery & Development Through Transformative Technologies & Overcoming Strategic Challenges
A concise report featuring insights from the prominent thought leaders of Biologics 2024
Exploring Innovative Approaches Throughout the CGT Development Journey
A Concise Report Featuring Insights From The Prominent Thought Leaders Of Cell UK
Unlocking the Future of Immune Cancer Therapy
A concise report featuring insights from the prominent though leaders of Immuno 2024.
Stem Cell Therapy
Zebrafish Models May Hold the Answer to Cell Dedifferentiation
Traditionally, cell fate and differentiation were considered to be a one-way journey. However, recent research using animal models like zebrafish has challenged this perspective.
Oligo Chemistry
Transforming Oligonucleotide Manufacturing: A Transformative UK Collaboration
A new collaboration from the Medicines Manufacturing Innovation Centre is looking to change the face of oligonucleotide development.
Drug Discovery & Development
AstraZeneca and Daiichi Sankyo Share Results of IO Combination Therapy in Ib Clinical Trial
Preliminary results from phase Ib clinical trial, TROPION-Lung02, evaluating the antibody drug conjugate datopotamab deruxtecan in combination with pembrolizumab.
Tumour Microenvironment
T Cell Atlas of Tumour Microenvironment Identifies Previously Unknown Cell State
The atlas provides valuable insights into T cell phenotypic states across various cancer types, paving the way for biomarker discovery and the development of improved therapeutic strategies.
Drug Discovery & Development
Monoclonal Antibodies: Guided Missiles in the Battle Against Cancer and More
Monoclonal antibodies (mAbs) have emerged as highly promising and versatile treatments for various diseases, particularly cancer.
Antibody & Protein Engineering
Unravelling the Link Between Type 2 Diabetes and Proteins
In honour of this week marking Type 2 Diabetes Prevention Week, we take a look at the intricate link between the disease and proteins.
Gene Therapy Development
Wilhelm Johannsen, Beans, and the Origins of Genotype and Phenotype
We spend a lot of time discussing new cell and gene therapies, as well as their implications for future treatment. But where did the term ‘gene' come from?
Peptide Chemistry
The Power of Collaboration: How The Sustainable Healthcare Coalition Measures the Impact of Sustainable Healthcare
The Sustainable Healthcare Coalition (SHC) emphasises the importance of collaboration with industry to address climate change in healthcare.
3D Cell Culture
3D Cell Cultures: From Disease Modelling to Toxicology
3D cell modelling can help develop understandings of disease pathologies, facilitating the investigation of how tissues react to certain treatments without causing undue harm or risk to the patients who need them.
Drug Discovery & Development
Identifying highly potent TNF-?-secreting T cells from blood samples in 7 hours using the Xdrop® double-emulsion droplet-based workflow
Bulk functional assays of immune cells miss highly potent cells within the population. This Xdrop workflow reveals highly potent TNF-?-secreting T cells in a human blood sample.
Drug Discovery & Development
Quantifying individual cells that secrete IFN-?, TNF-?, or both cytokines in a single-cell, drop®-based workflow
This Xdrop workflow enables rapid, multiplex quantification of the individual immune cells in a population that are secreting one or more cytokines. The results for single-cell format multiplex and singleplex assay concurred and were reproducible.