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Microbiome

New Research into Newborn Gut Microbiome Identifies Three “Pioneer Bacteria” for Babies’ Microbiota Development

The researchers analysed high-resolution genomic information from over 1,200 babies and identified three pioneer bacteria that drive the development of the gut microbiota.
Drug Discovery & Development

Insilico Medicine and Inimmune Pen Collaboration for AI-Powered Immunotherapy Discovery

The two biotechs are working together to overcome specific hurdles in the immunotherapy drug discovery process.
Stem Cell Therapy

Kyoto University Hospital Explores the Potential of Treating Type 1 Diabetes Using Induced Pluripotent Stem Cells

Kyoto University Hospital aims to develop a treatment for severe Type 1 diabetes using induced pluripotent stem cells (iPSCs) reprogrammed to function as pancreatic islet cells.
Regulatory

Regeneron’s Bispecific Gets EU Approval After FDA Rejection

The approval means that the bispecific antibody odronextamab can be used to treat adult patients with relapsed or refractory follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) in the EU.
Antibody & Protein Engineering

Absci to Collaborate with the Memorial Sloan Kettering Cancer Center to Develop Biologics using AI

The two organisations will work side by side on up to six programmes which will develop new cancer drug candidates using AI.
Antibody-based Therapies

MSD to Acquire Bispecific Antibody From Curon in Bid to Diversify Portfolio

The novel investigational clinical stage bispecific antibody targets CD3xCD19 to engage T cells with malignant B cells.
Peptide Chemistry

RSC 'Emerging Technologies' Award Goes to Solid Phase Peptide Synthesis Group

The novel peptide synthesis protocol allows the synthesis of multiple peptide fragments on a single bead.
Gene Therapy Development

Jaguar Gene's JAG201 Therapy Trial for SHANK3 Haploinsufficiency Receives FDA Approval

JAG201 gene replacement therapy available to both child and adult patients is now in Phase I clinical trial.
Immunotherapy (Non-Oncology)

CAR T Beyond Cancer: Applying the Cell Therapy for Lupus and Other Autoimmune Diseases

Can CAR T, which has had successes in immuno-oncology, be applied to reset the immune system of autoimmune disease patients?
Cell Therapy Development

Exploring Innovative Approaches Throughout the CGT Development Journey

A Concise Report Featuring Insights From The Prominent Thought Leaders Of Cell UK
Regulatory

FDA Fast Track ADC for Patients with Triple Negative Breast Cancer

The fast track designation means that the clinical development and regulatory milestones of the drug candidate are likely to progress much faster.
Gene Therapy Development

Reshaping Genome Editing: Doudna & Charpentier, the Founders of CRISPR/Cas9 and Their Legacy

In 2020 Jennifer Doudna & Emmanuelle Charpentier were awarded the Nobel Prize in Chemistry for discovering the revolutionary gene-editing tool CRISPR/Cas9. This article shines a spotlight on their remarkable achievements and addresses current applications and future opportunities for CRISPR/Cas9.

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