Resources

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Stem Cell Therapy

Wiping an iPS Cell's Epigenetic Memory With TNT

Transient-native-transient reprogramming enables researchers to sidestep the differentiation quirks which can complicate the use of induced pluripotent stem cells by resetting their epigenetic memory.
Bioanalysis

Biologics Market Trends and Predictions: New Horizons Beckon

Here, we outline some of the main trends anticipated in market growth and development for biologics in the next few years. The global biologics market is predicted to exceed $600bn by 2032, driven by demand for personalised treatments for chronic diseases.
Immuno-Oncology

iBio Reports Antibody Hat-Trick in its In Vivo IO Programs

Significant progress in iBio's in vivo preclinical programs with positive data from three antibody candidates: anti-EGFRvIII, CCR8, and TROP-2 x CD3.
Biomarkers & Precision Medicine

Exploring Oncology Biomarkers in Early Clinical Trials and Precision Medicine: Challenges and Opportunities

The importance of validating hypotheses, understanding the biology of cancer progression, and utilising biomarkers in early screening to stratify populations and improve clinical endpoints.
Stem Cell Therapy

Lipid Found in Breast Milk May Reduce Cerebral Palsy in Infants

A study from Duke University found that a lipid present in breast milk promotes a process leading to the generation of new brain cells, which could potentially aid in the repair of damaged white matter in infants with cerebral palsy.
Immuno-Oncology

Using Mouse Models for Preclinical Immuno Oncology

Unveiling advancements in preclinical immuno-oncology: Exploring humanized mouse models and human knock-in mice for targeted cancer therapies.
Oligo Chemistry

Targeted Delivery with FORCE: Novel Approaches in Oligo Therapeutics

How are oligo therapeutics revolutionising genetic disease treatments through precise targeting and transformative therapies? In this article, we explore how they provide precise gene expression interference for untreatable conditions by directly targeting disease-associated proteins and genetic mutations.
Manufacturing & Bioprocessing

Sustainability in Cell Therapy Manufacture: Improving Process Efficiency for Cell Line Development

Improving process efficiency is a key approach to factor in when looking at how cell therapy manufacture can be made more sustainable.

How Will Commercialisation Impact COVID-19 Vaccine Prices in the US?

We take a look at how the commercialisation of COVID-19 vaccines in the US will impact the price of the vital therapeutic.
NextGen Therapeutics

WuXi Biologics and GSK Enter License Agreement for Bispecific Development

The Pharma giants have partnered to advance the development of bispecific T cell engaging antibodies using WuXi’s platforms.
Drug Discovery & Development

Another Partnership from Takeda and F-Star Therapeutics to Look for Antibody-Based Therapies

The collaboration includes an upfront payment, milestone-dependent funds, and commercial royalties for F-star.
Drug Discovery & Development

Immune Cell Types: Their Opportunities for Therapeutic Use in Oncology

An introduction to the various cell types in the immune system and the opportunities to harness them in immuno-oncology therapies.

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