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Microbiome

New Research into Newborn Gut Microbiome Identifies Three “Pioneer Bacteria” for Babies’ Microbiota Development

The researchers analysed high-resolution genomic information from over 1,200 babies and identified three pioneer bacteria that drive the development of the gut microbiota.
Drug Discovery & Development

Insilico Medicine and Inimmune Pen Collaboration for AI-Powered Immunotherapy Discovery

The two biotechs are working together to overcome specific hurdles in the immunotherapy drug discovery process.
Regulatory

Regeneron’s Bispecific Gets EU Approval After FDA Rejection

The approval means that the bispecific antibody odronextamab can be used to treat adult patients with relapsed or refractory follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) in the EU.
Antibody-based Therapies

MSD to Acquire Bispecific Antibody From Curon in Bid to Diversify Portfolio

The novel investigational clinical stage bispecific antibody targets CD3xCD19 to engage T cells with malignant B cells.
Immunotherapy (Non-Oncology)

CAR T Beyond Cancer: Applying the Cell Therapy for Lupus and Other Autoimmune Diseases

Can CAR T, which has had successes in immuno-oncology, be applied to reset the immune system of autoimmune disease patients?
Immunotherapy (Non-Oncology)

Scientists Develop First Mouse Model with Complete & Functional Human Immune System

The breakthrough in mouse models will allow researchers to study the human immune system in far greater detail at a far greater pace.
Cancer Vaccines

NHS Cancer Vaccine Launchpad to Give Thousands Access to Personalised Cancer Vaccines

NHS England aims to match up to 10,000 cancer patients to suitable personalised cancer vaccine clinical trials by 2030.
Biomarkers & Precision Medicine

AI-Enabled Predictive Biomarker for Patient Response to Immunotherapy Using Easy-to-Measure Features

The predictive biomarker does not require multi-omic or screening data, but rather routine clinical features.
Vaccines

H5N1 Bird Flu Outbreaks: Effect on Vaccines

H5N1 outbreaks in the US have mobilised pandemic preparedness mechanisms with stockpiling of avian flu vaccines.

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