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The latest in omics research, from discovery and multi-omics approaches through to diagnostics development
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Top R&D Stories of 2023
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Single Cell Analysis
Single-Cell Transcriptomics and Implications for COVID-19 Severity
The expression of the protein coding gene CXCR6 was observed to be significantly lower in patients with severe cases of COVID-19, suggesting a genetic correlation in severe cases.
Single Cell Analysis
Sparsely Connected Autoencoders: A Multi-Purpose Tool for Single Cell Omics Analysis
In this Commentary article, we explore the opportunity afforded by Sparsely Connected Autoencoders to transform data in a controlled way to enable the comprehension of hidden biological information in single-cell data. Autoencoders provide researchers with a simplified means of inspecting functional relationships among regulatory elements as transcription factors.
Single Cell Analysis
Single Cell Analysis of the Tumour Microenvironment: Improving Understandings of Immune Contexts
This Discussion Group Report investigates some of the various applications of single cell analysis, and explores the differences in its utility relative to other analysis techniques such as spatial transcriptomics.
Single Cell Analysis
Single Cell Proteomics: Advancements and Potential
Our April 2022 Omics Series discussion group focused on the potential and future of single-cell proteomics.
Single Cell Analysis
Single Cell Proteomics: Sample Preparation and Tissue Selection
Single-cell proteomics has developed quickly, despite being a relatively new field. NanoPOTS and FACS are being used to improve proteome coverage and minimise sample size.
Single Cell Analysis
Characterization of HepaRGŽ cells grown in 2D or 3D culture at single cell level using the cellenCHIP 384-3RNA-Seq Kit
The emergence of single-cell sequencing has opened a new field in analytical biological approaches particularly allowing to uncover cell-to-cell heterogeneity of 3D cellular models and preventing incomplete conclusions drawn from bulk cell populations
Single Cell Analysis
Single Cell Transcriptomics: Computational Analysis and Data Normalisation
Due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, single cell analysis opens up many new possibilities.
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