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A Concise Report Featuring Insights From The Prominent Thought Leaders Of Discovery & Automate 2024
Paving the Way For Animal Free Models by Leveraging 3D Cell Culture, Organoids & Organ Modelling
A Concise Report Featuring Insights From The Prominent Thought Leaders Of 3D Cell Culture & Organ Modelling 2024
Top R&D Stories of 2023
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Molecular Drug Design
Artificial Intelligence for Drug Design and Discovery
Artificial intelligence and machine learning could be an invention comparable to electricity, so what does the future hold for its use in drug discovery?
Molecular Drug Design
Explainable AI: Addressing Challenges for Machine Learning Implementation
There are many reasons why it is crucial to understand how an AI-enabled system has led to a specific output. Explainability can help developers ensure that the system is working as expected, meet regulatory requirements, or reveal the importance and effects of data previously deemed unimportant by humans.
Molecular Drug Design
Machine Learning in Clinical Data Analysis: From Alan Turing to Modern-Day Data Sequencing
Some of the biggest current focuses of machine learning and AI research and development include testing clinical scenarios to identify the patients who will benefit most from treatment. One of the main goals for researchers is increasing the transparency and understanding underpinning data sharing and AI technology.
Automation
Smart Labs & Automation: Digital Literacy User Friendliness
The pharmaceutical industry is working on improving the usability of automation platforms but challenges remain.
Organ Modelling
Organoids: Robust Media to Culture Intestinal, Hepatic, Pancreatic, Kidney, Airway, and Cerebral Organoids
One of the most impactful advances in stem cell research of the past decade has been the development of organoid culture techniques.
Chemical Biology
Protein Degradation – Discussion Group Report
Progress in protein degradation has accelerated in the past few years, and 2021 saw several breakthroughs. Efforts to target STAT3, however, have proven to be especially challenging.
Target Discovery
Drugging KRAS: a Once ‘Undruggable’ Target
RAS mutations are the most common subfamily of oncogenes, so finding inhibitors could be extremely valuable to oncology research. However, they also make for particularly difficult targets. Andreas Mantoulidis explains how BI have been attempting to ‘drug the undruggable.’
Molecular Drug Design
Pharma Manufacturing: Digitalization and Industry 4.0
Digital tools to boost productivity and optimise pharma manufacturing are becoming increasingly prevalent through smart sensors, AI, ML, virtual reality, and cloud computing. Digital transformation is here for Pharma, and it is changing companies' priorities towards digital solutions.
How MSD’s Discovery Centre is Fighting Age-Related Neurodegeneration
How does the MSD group find its targets for neuroscience drugs?
Molecular Drug Design
Unlocking Innovation In Drug Discovery With IPU Powered AI
Presented by Alex Titterton, Field Applications Engineer, Graphcore
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