The latest in cell & gene research, from advanced therapies through to the latest developments in cell & gene research, therapies & manufacturing

Stem Cell Development & Manufacturing

In Conversation with Stephen Sullivan, COO of iPSirius

Cell & Gene 2024 Conference Producer Anya Chuykov met with Stephen Sullivan, COO of iPSirius, to discuss the advancements being made by iPSirius, and their unique proprietary technology working to treat aggressive forms of cancer.
Stem Cell Development & Manufacturing

Comparing Allogeneic and Autologous Stem Cell Transplantation Approaches

While both allogeneic and autologous cell therapies have seen a recent boom, the two approaches differ in terms of scale and customisation.
Stem Cell Development & Manufacturing

Applications of Stem Cells in Personalised Medicine

Novel applications of stem cells drive personalized medicine, tailoring treatments to each patient's unique profile. Explore groundbreaking applications for more effective, individualized therapies.
Stem Cell Development & Manufacturing

Spinal Stem Cells 'Lure' Tumours to the Spine, Study Shows

An animal model study suggests that cells produced by breast cancer preferentially metastasize to the spine over other bones in the body, with key proteins identified as affecting spinal tropism.
Stem Cell Development & Manufacturing

Wiping an iPS Cell's Epigenetic Memory With TNT

Transient-native-transient reprogramming enables researchers to sidestep the differentiation quirks which can complicate the use of induced pluripotent stem cells by resetting their epigenetic memory.
Stem Cell Development & Manufacturing

Lipid Found in Breast Milk May Reduce Cerebral Palsy in Infants

A study from Duke University found that a lipid present in breast milk promotes a process leading to the generation of new brain cells, which could potentially aid in the repair of damaged white matter in infants with cerebral palsy.
Stem Cell Development & Manufacturing

Zebrafish Models May Hold the Answer to Cell Dedifferentiation

Traditionally, cell fate and differentiation were considered to be a one-way journey. However, recent research using animal models like zebrafish has challenged this perspective.
Stem Cell Development & Manufacturing

Induced Pluripotent Stem Cells to be Manufactured on the ISS

With evidence suggesting that microgravity conditions may be best for growing and developing pluripotent stem cells, a team of astronauts aboard the International Space Station are set to test this hypothesis.
Stem Cell Development & Manufacturing

Gene Knockout Mice in Disease Modelling

Over the past 50 years, rare disease research has paved the way for medical breakthroughs such as allogeneic stem cell transplantation. Other focuses have included the identification of potential drug targets by analysing cellular and molecular pathways.
Stem Cell Development & Manufacturing

Beating the System with Advanced High Throughput and Real-Time Analytics for Biopharmaceutical Manufacturing

Can advanced analytical processing and real-time data monitoring conquer the complexity of Bio-pharmaceutical manufacturing? We ask Udayanath Aich, Director at Bristol Myers Squibb.
Stem Cell Development & Manufacturing

Combinatorial Culture Technology for Stem Cell Therapy Applications

How can combinatorial screening of diverse variables in process development optimise cell and gene therapies? Marina Tarunina, Research Director at Plasticell, investigates.
Stem Cell Development & Manufacturing

Potency Assays for Thalassemia and Sickle Cell Disease Gene Therapy Drug Products

In this Commentary article, we explore how reductions in testing complexity can improve access to hematopoietic stem cell therapies for patients with blood disorders. The provision of safe, effective therapies will help to ameliorate the worst impacts of these disorders for patients and afford them a better quality of life.

Subscribe to Our Newsletter

Sign up for our monthly newsletter to
keep up with all things cell & gene