October 2023

Science Exchange Topics

• The qualification of biomarkers & clinical biomarker case study
• Current trends in FDA licencing
• Correlating US trends with EU trends in submission handling
• Incorporating digital pathology and imaging approaches
• Addressing diagnostic clearances in submissions
  
  

Science Exchange Leader

• Steven Piccoli: Head of Clinical Biomarkers, SPARC 

September 2023

Science Exchange Topics

• Blood-based biomarker analysis 
• Standardising data collection and monitoring approaches
• A need for new cardiac and complementary biomarkers 
• Applications in monitoring neurodegenerative disease
• Advantages and limitations in disease detection and prognosis

Science Exchange Leaders

• Mike Baratta: Senior Director and Head of Mass Spectrometry at Takeda 
• James Snider: President at Critical Diagnostics

June 2023

Science Exchange Topics:

• Shaping the healthcare environment around precision medicine
• Partnering strategies for working between companies
• The current regulatory environment for medical genetics
• Overcoming hurdles associated with information sharing
• Biggest anticipated changes and focuses for future development

• Vseolod Makeev: Head of Department, The Vavilov Institute of General Genetics

May 2023

Science Exchange Topics:

• New opportunities in immuno-oncology biomarkers
• Necessary approaches for implementing new biomarker technologies
• Alternative options as bacterial and viral therapies
• Cost-effective approaches to immuno-oncology in healthcare
• Distinguishing between immune responses to therapy and cancer

• Alexandra Sevko: Director of Translational Research, Prokarium

May 2023

Science Exchange Topics:

• Creating data analysis workflows for deconvoluting processes
• Molecular histopathology: approaches to integration 
• Best-practice strategies for data interpretation and interrogation
• Cooperating with computational biologists, molecular biologists and pathologists
• Appropriate resource management in project execution

• Priyank Patel: Senior Scientist, Boehringer Ingelheim

April 2023

Science Exchange Topics:

• Incorporating biomarkers into drug development and clinical trials for neurodegenerative diseases
• The use of surrogate tissues for brain biomarkers
• What technologies are being developed to characterise other tissue and other matrixes 
• Emerging technologies to enable access to rare tissue
• Multimodal biomarkers in the detection of neurological disorders
• The value of translational biomarker research

• Vincent Mikol: Precision Medicine Head, Sanofi
• Jennifer Barnett: Chief Executive Officer, Monument Therapeutics
• Kira Holmström: Head of Biomarker Research, Herantis Pharma

February 2023

Science Exchange Topics:

• New exploration points for digital biomarkers in oncology
• Regulatory challenges in digital health technologies
• Validating new digital health indicators: proof of being ‘fit for purpose’
• Digital health technologies and their role in monitoring patient outcomes
• AI and ML in digital biomarkers: opportunities and constraints 

• Derek Hill: Professor of Medical Imaging Science, UCL
• Alina Ainbinder: Principal Scientist, Takeda 

February 2023

Science Exchange Topics:

• Biomarker development: early-stage clinical development versus late-stage clinical development
• Best-practice approaches for assessing clinical response in patients
• Advances in imaging modalities for biomarker analysis
• Current hurdles for biomarkers in clinical development
• Anticipated breakthroughs in the next five to ten years

• Xuemei Zhao: Senior Principal Scientist, Merck
• Simone Filostro: Director of Cell Biology and Translational Medicine, Kite Pharma

 November 2022 

Science Exchange Topics:

• Patient Engagement in Biomarker Clinical Trials
• Clinical Adoption of New Biomarkers in Patient Care
• Awareness of Clinical Utility of Biomarker Patient Testing for New Therapeutics

Science Exchange Leader:

• Christopher Conn, Director, Diagnostics Strategy at Amgen
• George Kumar, Director and Medical Lead- Diagnostics & Digital Pathology at BMS

 October 2022

Science Exchange Topics:

• Effective tracking of patient recovery
• Overcoming the challenges in early disease detection
• Remote monitoring of patients

Science Exchange Leaders:

• Beverley Patterson, Clinical Science Director at Ono Pharma UK Ltd
• George Kumar, Director and Medical Lead- Diagnostics & Digital Pathology at BMS
• Steven Piccoli, Associate Vice President at Sun Pharmaceutical Advanced Research Center