In this Commentary article, we explore the opportunity afforded by Sparsely Connected Autoencoders to transform data in a controlled way to enable the comprehension of hidden biological information in single-cell data. Autoencoders provide researchers with a simplified means of inspecting functional relationships among regulatory elements as transcription factors.

This Insight article explores some of the key applications of mass spectrometry imaging across the medical and pharmaceutical landscape. With the field seeing constant rapid development, mass spectrometry is an essential tool for current and future research in healthcare.

This Discussion Group Report investigates some of the various applications of single cell analysis, and explores the differences in its utility relative to other analysis techniques such as spatial transcriptomics.

Erin Newburn, Senior Director, Field Applications Scientist at Personalis, Inc. showcases the Personalis NeXT Platform ®, a tumour profiling solution for both tissue and liquid biopsies at Biomarkers UK 2022.

Anna Lyubetskaya, Senior Principal Scientist at Bristol Myers Squibb, leads a discussion on the industry landscape and ‘Current Status of Omics-Based Biomarkers.’

Quantitative mass spectrometry offers a clinical tool for the discovery of biomarkers, which can be vital in helping to treat certain cancers. In this Commentary article, we explore the applications of mass spectrometry for the identification of triple negative breast cancer and some of the implications for future research.

Senior representatives from Ultivue, Genentech, and GSK discuss the current trends and opportunities in enabling the future of multi-omics-based analysis.

Miao-Ping Chien, Principal Investigator at Erasmus University Medical Center and Oncode Institute, explains what the Berlin meet has to offer and outlines her predictions for the future of spatial technology.

Long Read DNA Sequencing has the potential to help diagnose several diseases and disorders. Recent advancements mean that long-read sequencing is no longer an expensive, low throughput, error-prone process.

In this Insight article, we explore some of the challenges and new innovations concerning spatial analysis of the tumour microenvironment. One of the key focuses for ongoing studies is the retention of spatial information, which enables researchers to identify distinct tumour subtypes.

In this Discussion Group Report, we investigate some recent applications of long- and short-read sequencing technologies. Continued improvements and advancements in the field mean sequencing errors are increasingly a thing of the past, while the portability of some new units makes them ideal for work in the field.