Fast-Track Formulation with Biologics Screening in a Snap

As subcutaneous delivery of high-concentration biologics becomes more popular, optimizing their formulations becomes more complicated. Some excipients play better with one antibody, not another, or only help under specific conditions. Testing formulations at high protein concentration makes lower sample consumption and efficient assays a must-have. High-throughput, low volume solutions, designed for biologics, will speed up those formulation studies. Here, we present a case study on how to prepare monoclonal antibodies at high and low concentrations with some common excipients and screen for effects on quality, stability, and viscosity. 

The case study will illustrate how to produce all this data seamlessly, allowing the researcher to rate and rank formulations for their influence on the analyte and to quickly narrow down the optimal excipients.