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All Discovery Content

Bringing you the latest research in Drug Discovery In New Modalities, Integration Of DEL, Covalent Inhibitors, Protein Degradation Technologies, Computational Drug Design & Automation Strategies and more, through a range of Speaker Interviews, Industry Insights, and Expert Opinions.
Industry Spotlight
Targeting Novel E3 Ubiquitin Ligases: Carles Galdeano, Professor, University of Barcelona
We discuss working on PROTACs, targeting novel E3 ubiquitin ligases, and Dr Galdeano's spin out Oniria Therapeutics.
Edited by Tom Cohen |
01 December 2023
Targeted Protein Degradation
Industry Spotlight
Talking TPD with Ben Cross, CTO and Head of Platform at PhoreMost
Delving into PhoreMost's role in targeted protein degradation, the innovation behind the SITESEEKER platform, and the challenges and breakthroughs in the dynamic field of drug discovery.
Edited by Tom Cohen |
22 November 2023
Targeted Protein Degradation
Insight Article
Challenges and Opportunities in Targeted Protein Degradation: Current and Future Strategies
Discussing the challenges and strategies in targeted protein degradation (TPD), a promising therapeutic modality with the potential to drug difficult or "undruggable" protein targets.
Edited by Tom Cohen |
01 August 2023
Targeted Protein Degradation
Industry Spotlight
Drugging the Undruggable: Targeted Protein Degradation
Using the body's mechanisms to degrade proteins not amenable to traditional small molecule approaches, offering the potential to "drug the undruggable" and permanently destroy target proteins.
Edited by Tom Cohen |
19 June 2023
Targeted Protein Degradation
Video Content
Video Q&A
Interview with Yusuke Tominari, Co founder and CEO of Fimecs
Yusuke will be giving a keynote presentation at Discovery Europe 2023 titled 'Targeted Protein Degradation And Addressing Undruggable Targets'.
Edited by Tom Cohen |
26 May 2023
Targeted Protein Degradation
Video Content
Video Q&A
Interview with Felix Hausch, Professor for Structure Based Drug Research at TU Darmstadt
Felix will deliver his presentation 'Clues for Molecular Glues' at Drug Discovery Europe 2023.
Edited by Tom Cohen |
12 May 2023
Targeted Protein Degradation
Discussion Group Report
The Bioavailability of Oral PROTAC Molecules for ER+ Breast Cancer
Thomas Hayhow, Associate Principal Scientist at AstraZeneca presents his company’s efforts in delivering PROTACs orally.
Edited by Tom Cohen |
25 May 2022
Targeted Protein Degradation
Commentary
PROTACs: “Exciting Opportunities to Explore New Biology”
A Senior Director at AstraZeneca takes us through how the company synthesises and validates novel PROTACs.
Edited by Tom Cohen |
13 May 2022
Targeted Protein Degradation
Insight Article
Getting PROTACs into the Clinic: The Challenges
Oxford Global’s protein degradation panel discussion brought together leading experts in the field to talk about bringing PROTACs to clinical trial endpoints.
Edited by Tom Cohen |
21 April 2022
Targeted Protein Degradation
Discussion Group Report
Protein Degradation – Discussion Group Report
Progress in protein degradation has accelerated in the past few years, and 2021 saw several breakthroughs. Efforts to target STAT3, however, have proven to be especially challenging.
Edited by Oliver Picken |
18 February 2022
Targeted Protein Degradation

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