Matthew Brown, Chief Scientific Officer, Genomics England

A globally recognized leader in genomic medicine, Professor Matthew Brown will take the stage to discuss groundbreaking advancements in rare disease diagnostics. His presentation, "Improving Rare Disease Diagnostic Performance Using Multiomics," will explore how new technologies—including long-read DNA sequencing, transcriptomics, proteomics, and metabolomics—can improve diagnostic rates beyond the 30% currently achieved with short-read whole genome sequencing. He will also share future perspectives from Genomics England and the broader industry on how multiomic approaches can drive innovation in precision medicine research.
Professor Brown will be available across the networking breaks on Day One - don’t miss the chance to connect with him over a coffee and explore the future of precision diagnostics. 

Professor Sir Mark Caulfield, Vice Principal for Health, Queen Mary’s Faculty of Medicine and Dentistry; CEO, Barts Life Sciences; President, British Pharmacological Society

A visionary in genomic medicine, Professor Sir Mark Caulfield has played a pivotal role in shaping the future of precision medicine and genomic healthcare. Mark was instrumental in delivering the groundbreaking 100,000 Genomes Project, which has transformed rare disease and cancer diagnostics, delivering life-changing results for patients. In recognition of his leadership in this project, he was awarded a knighthood in 2019.
In this engaging fireside chat to close Day 1, Professor Caulfield will reflect on his journey at the forefront of genomic medicine, discussing the lessons learned from large-scale sequencing initiatives, the future of precision healthcare, and the next wave of genomic innovation. With expertise spanning clinical pharmacology, rare disease research, and translational medicine, his insights promise to be both strategic and inspiring.