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The latest in omics research, from discovery and multi-omics approaches through to diagnostics development
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Top R&D Stories of 2023
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Genome Editing
The Applications of CRISPR in Optimising Animal Models for Human Disease Research
CRISPR-based animal models expedite drug development by enhancing accuracy, replicating human physiology, reducing time and cost, aiding in predicting treatment efficacy, and addressing safety concerns in clinical trials.
Genome Editing
Celebrating the Achievements of Barbara McClintock, Discoverer of Mobile Genetic Elements and Gene Transposition
To date, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates. Of these laureates, just 12 have been women. This article looks at one of those 12 women and celebrates her contributions to the field of genetics. Her name is Barbara McClintock.
Genome Editing
New Human Pangenome Capturing More Genomic Diversity Released
The human pangenome contains genetic data from 47 people across Africa, Asia, Europe, and the Americas, and offers a more holistic cross-section of the planet’s genetic diversity.
Genome Editing
Transforming Genomics with AI
Artificial Intelligence (AI) and accelerated computing enable new frontiers in genome sequencing workflows.
Genome Editing
On & Off-Target Genome Editing Techniques
Richard Stanton, Professor of Virology at Cardiff University, presents the latest on and off-target genome editing techniques.
Genome Editing
Machine Learning Algorithm Measures Prime Editing Efficiency
Wellcome Sanger Institute propose a new machine learning algorithm for predicting genome editing efficiency for the CRISPR-Cas9-based approach of prime editing.
Genome Editing
Recent Advances and the Future Landscape of Genome Editing For Disease Models And How This Has Helped Us Gain Insight Into Disease Biology
In Conversation With Laralynne Pryzbyla, Adjunct Assistant Professor at UCSF & UC Scientific Director, Laboratory for Genomics Research
Genome Editing
Regulation & Policy: Interview with John Parrington, Associate Professor of Cellular and Molecular Pharmacology, University of Oxford
John Parrington, Associate Professor of Cellular and Molecular Pharmacology & Fellow of Worcester College, University of Oxford, discusses the regulatory challenges and opportunities of genome editing.
Genome Editing
Policy Issues for Responsible Genomics Research
Responsible genomics research is vital to ensuring the advancement of health for society. But what are the ethical, social, and legal considerations that go into genomics-based decision making?
Genome Editing
FDA and NIH Sign Interagency Collaboration Agreement to Advance Proteogenomics Research
A memorandum of understanding has been reached between the U.S. Food and Drug Administration (FDA) and the National Cancer Institute (NCI) to provide a framework for solving complex problems in molecular characterisation and classification of tumours.
Genome Editing
Novel Genome Editing Techniques: What Will Come Next after CRISPR-Cas9?
The gene editing field has exploded in the last ten years, with methods such as CRISPR-Cas9 becoming well-established in the pre-clinical sphere. However, complications in clinical applications have led some researchers to explore alternatives.
Genome Editing
Genome Editing Technologies: Pioneering Approaches in Healthcare
Current and upcoming gene editing technologies, such as prime editing and cell line models, have huge potential in applications such as cancer treatment. With the field constantly witnessing new breakthroughs and advances, genome modification holds a lot of promise for the future.
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