In-Depth

The In-Depth page consists of Insight Articles, Commentaries, C-level Q&As, Discussion Group Reports, and Survey Reports.

Insight Article
Explore the groundbreaking advancements in inhaled drug delivery, a transformative approach that promises enhanced efficacy and patient convenience
Edited by Guillaume Alonso |
06 December 2023
Inhaled Drug Delivery
Insight Article
Edited by Guillaume Alonso |
15 September 2023
Drug Formulation, Formulation & Delivery Series, Oligonucleotides
Insight Article
Novel technologies in drug development, including personalized medicine manufacturing, cyclic peptides, and continuous manufacturing methods.
Edited by Tom Cohen |
13 September 2023
Drug Formulation
Commentary
Pfizer continues to explore even greener alternatives to traditional lyophilisation methods like air cooling in its pursuit of environmental sustainability.
Edited by Tom Cohen |
13 September 2023
Drug Formulation
Insight Article
Optimising drug delivery, stability, and patient outcomes through considerations such as formulation simplicity, critical temperatures, excipient selection, and the use of digital approaches.
Edited by Tom Cohen |
24 May 2023
Drug Formulation
Insight Article
What needs to be considered for RNA drug delivery? From the stability of LNPs, to proteins in the blood, to descant selection and packaging.
Edited by Tom Cohen |
17 May 2023
RNA Formulation & Delivery
Insight Article
Inhaled biologics are being evaluated as an alternative to injections for treating rare and serious diseases. Experts touch on several challenges including making stable and safe formulations of inhaled biologics.
Edited by Tom Cohen |
13 April 2023
Inhaled Drug Delivery
Insight Article
Cholesterol oxidation, working with regulators, drug loading nanoparticles, and functional excipients for specific pathways.
Edited by Tom Cohen |
21 March 2023
Drug Formulation
Insight Article
An expert panel of formulation scientists discuss the challenges and solutions within the formulation development for biologics.
Edited by Tom Cohen |
16 January 2023
Drug Formulation
Discussion Group Report
Our discussion group on new delivery technologies considered novel and imaginative techniques for delivering drugs to their active sites.
Edited by Tom Cohen |
04 January 2023
Drug Delivery
Insight Article
Key opinion leaders from AstraZeneca and King’s College London present their findings on cutting-edge approaches to nano delivery.
Edited by Tia Byer |
08 December 2022
Drug Delivery
Insight Article
Liquid formulations of medicines exist to serve the needs of vulnerable patients. What are their applications? And what challenges are they facing, both in industry and on the market?
Edited by Tom Cohen |
17 November 2022
Drug Delivery
Discussion Group Report
Our Inhaled Therapeutics discussion group brought together key experts in the field of dry powder formulation to discuss their research into both formulation and process.
Edited by Tom Cohen |
09 November 2022
Inhaled Drug Delivery
Commentary
Karsten Flügel of Merck Healthcare discusses how in-silico tools are used to optimise process development for drug production.
07 November 2022
Drug Formulation
Insight Article
Our expert panel discuss the process of ensuring that inhalation devices are not burdensome to use.
Edited by Tom Cohen |
31 October 2022
Inhaled Drug Delivery
Commentary
When designing drug-delivery devices, the patient must be at the centre of the development process. Nélio Drumond of Takeda Pharmaceuticals discusses how this patient-centric approach allows the design to maximise efficiency and efficacy.
17 October 2022
Inhaled Drug Delivery
Discussion Group Report
Our Formulation discussion group this September focused on the unique challenges of developing formulations for biotherapeutics
Edited by Tom Cohen |
10 October 2022
Drug Formulation
Insight Article
Our panel discussion from Formulation UK 2021 highlights protein aggregation, safety, and novel technologies.
Edited by Tom Cohen |
07 October 2022
Drug Formulation
Commentary
Using a combination of prevalent CSTDs with biologic molecules, we present a systematic approach to evaluate the risks and impact of CSTD to drug product quality, dose preparation, and dosing accuracy
09 September 2022
Drug Delivery
Insight Article
RNA therapeutics have great potential, as evidenced by the success of Pfizer-BioNTech and Moderna’s COVID vaccines. One difficulty that may stunt their success lies in their delivery challenges.
Edited by Tom Cohen |
08 September 2022
RNA Formulation & Delivery
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