Resources

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Chemical Biology

Targeting Novel E3 Ubiquitin Ligases: Carles Galdeano, Professor, University of Barcelona

We discuss working on PROTACs, targeting novel E3 ubiquitin ligases, and Dr Galdeano's spin out Oniria Therapeutics.
Organ Modelling

Spheroids, Assembloids Could Unlock High Throughput Screening of Neuro Drugs

These spheroids can mimic different sections of the human brain based on their cell-type composition, and promisingly could enable high-throughput screening of neurology drugs.
Chemical Biology

Talking TPD with Ben Cross, CTO and Head of Platform at PhoreMost

Delving into PhoreMost's role in targeted protein degradation, the innovation behind the SITESEEKER platform, and the challenges and breakthroughs in the dynamic field of drug discovery.
Target Discovery

Pivot Park Screening Centre: We Help You to Accelerate Drug Discovery

Are you looking for lead candidate compounds for your target or cellular phenotype, and do you want your drug discovery program to be more efficient, both in terms of time and cost?
Molecular Drug Design

Interview with Sridevi Nagarajan, Head Digital Regulatory Strategy at AstraZeneca

AstraZeneca’s Sridevi Nagarajan discusses the importance of artificial intelligence, strategic collaboration, and the role of the metaverse in unlocking the future of digital regulatory.
Pharma Data

Funding Opportunity Announced for Generating Real-World Evidence in Regulatory Decision-Making

The U.S. Food and Drug Administration (FDA) is encouraging pharmaceutical developers to submit real-world evidence in support of regulatory applications.
Organ Modelling

Vascular Organoids used to Model the Impact of COVID-19 on Circulation

Researchers have used vascular organoids to look at the impact of SARS-CoV-2 on blood circulation, which has led to the discovery of a potential therapeutic target.
Medicinal Chemistry

Biophysical Tools for the Design and Development of PROTACs

Protein degradation has emerged as a promising new field of therapeutics. What are biophysical tools are employed for the characterisation of these drugs?
Chemical Biology

Challenges and Opportunities in Targeted Protein Degradation: Current and Future Strategies

Discussing the challenges and strategies in targeted protein degradation (TPD), a promising therapeutic modality with the potential to drug difficult or "undruggable" protein targets.
Automation

Smart Labs for Smart Research: Advanced Robotic Solutions Through Automated Development

‘Smart labs’ is a term that is incredibly prevalent in the world of pharma data management. But what are the building blocks of these laboratories that are proving ever-more important in modern research?

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