The Westin St. Francis San Francisco on Union Square is centrally located in the heart of downtown San Francisco. Positioned directly on Union Square, it offers excellent transit connections via BART and Muni, and is within close proximity to key regional rail and airport links. The hotel is ideal for both business and leisure travelers, surrounded by shopping, theaters, and major city attractions.

By Air

San Francisco International Airport (SFO) –
From SFO, take the BART (Bay Area Rapid Transit) directly to Powell Street Station (about 30 minutes). Exit the station and walk north on Powell Street for 2 blocks to Union Square, the hotel is located on the west side of the square. BART fares range from $10–$12 depending on time of day. A taxi or rideshare typically takes 25–40 minutes, costing approximately $40–$60 depending on traffic.

Oakland International Airport (OAK) –
Take the BART from the Oakland Airport BART station via the Coliseum station to Powell Street Station (about 40–45 minutes total). From there, walk to the hotel as above. Fares range from $11–$13. A taxi from OAK can take 35–50 minutes and cost $55–$75.

San Jose International Airport (SJC) –
Take the Caltrain from San Jose Diridon Station to San Francisco (4th & King Station), then connect via Muni Metro or taxi to Union Square. Total transit time is about 1.5–2 hours. Driving or taxi from SJC typically takes 60–90 minutes and costs around $90–$130.

By Public Transport

BART –
The nearest BART station is Powell Street, just a 5-minute walk from the hotel. BART provides direct access to SFO, OAK, the East Bay, and the Mission District.

Muni Metro –
The Powell Street Station also connects with Muni Metro lines, including the J, K, L, M, N, and T lines. This allows for convenient travel within San Francisco.

Muni Buses & Cable Cars –
Numerous Muni bus routes and two  cable car lines stop directly in front of the hotel on Powell and Geary Streets, providing scenic transit options to Fisherman’s Wharf, Chinatown, North Beach, and more.

By Rail

Caltrain –
Caltrain service from the Peninsula and San Jose terminates at San Francisco (4th & King Station). From there, take Muni Metro or a short taxi/ride-share (10–15 minutes) to the hotel.

Amtrak –
Amtrak’s San Francisco-bound services arrive via a transfer at Emeryville Station, with a bus connection to downtown SF. Disembark at the Ferry Building or Transbay Terminal, then take Muni or taxi to the hotel.

By Car

From US-101 North (from SFO):
Take I-80 E toward Bay Bridge, exit at Seventh Street, turn left on McAllister, right on Hyde, then right on Geary Street. The hotel entrance is at 335 Powell Street, on Union Square.

From I-80 West (Bay Bridge):
Exit at Fremont Street, follow signs to Market Street, turn right onto 3rd Street, continue onto Kearny Street, then left onto Geary Street and right on Powell Street.

Parking

Valet parking is available at The Westin St. Francis, with overnight rates typically ranging from $80–$95 including tax. 

Nearby Parking Options –
Several public car parks are located within walking distance, including:

• Union Square Garage (333 Post St)

• Sutter-Stockton Garage (444 Stockton St)

Rates range from $4–$5 per hour, with daily maximums around $36–$40.

Accessibility

The Westin St. Francis is fully wheelchair accessible. For special access or drop-off needs, valet attendants can assist upon request.

Oxford Global has secured a number of bedrooms at The Westin St. Francis San Francisco at Union Square at a reduced conference rate: -

Sunday 26th October 2025 - $630 including taxes and fees

Monday 27th October 2025 – $630 including taxes and fees

*Please note: $30 supplement is applicable for double occupancy*

The final cut-off date to book bedrooms is Wednesday 24th September 2025– any bookings after this date are subject to availability and rates. Please note that any cancellations after the 25th September 2025 are subject to cancellation charges.

To book accommodation, please follow the link here.

We are closely monitoring the official guidance from health authorities, local governments, and the World Health Organization in order to support the health and well-being of our global community. The health and safety of our staff, customers and clients remains our number one priority.

As we continue to move forward with hosting our events in-person in 2026, we’ve added a series of Health & Safety guidelines and precautions in order to prepare for event safety. We carry out risk assessments for all our events to evaluate fundamental considerations and how to cover multiple risk scenarios.

Oxford Global has learned that third-party companies (recently EHotel Services, Business Travel Management/btravelmanagement and Exhibitors Hotel Reservations Services) are targeting conference attendees with a fraudulent hotel booking scheme.

Please note that none of these third-party companies are associated with Oxford Global in any way, nor have Oxford Global authorised them to use their names or trademarks on information they send out to attendees.

If you are contacted by a third-party company by phone or email using Oxford Global’s name or the name of Biomarkers & Precision Medicine US 2025 and offering accommodation services, we urge exhibitors and attendees to proceed with extreme caution before signing anything sent by these companies or entering into any conversation or replying to any emails sent from these third-party companies.